A sarcoma of 23 years' duration: symptom duration is not a reliable parameter to exclude malignancy

ABSTRACT

Hong Kong Med J 2012;18:250–2 | Number 3, June 2012
CASE REPORT
A sarcoma of 23 years' duration: symptom duration is not a reliable parameter to exclude malignancy
YL Lam, WY Ho, TP Ng, Amanda Kan, Tony WH Shek
Department of Orthopaedics and Traumatology, Queen Mary Hospital, Pokfulam, Hong Kong
 
 
This report describes a 31-year-old woman with a 23-year history of a right buttock mass that was otherwise asymptomatic, but was proven to be a low-grade fibromyxoid sarcoma (a fully malignant soft tissue tumour with a potential for distant metastasis). This case illustrates that a long-standing tumour does not necessarily imply a benign pathology. A vigilant approach should be taken for any tumours that are of significant size (larger than 5 cm).
 
Key words: Fibrosarcoma; Sarcoma; Soft tissue neoplasms
 
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Rhabdomyolysis associated with Mycoplasma pneumoniae pneumonia

ABSTRACT

Hong Kong Med J 2012;18:247–9 | Number 3, June 2012
CASE REPORT
Rhabdomyolysis associated with Mycoplasma pneumoniae pneumonia
Fahmi Y Khan, Hassan Sayed
Department of Medicine, Hamad General Hospital, Doha, Qatar
 
 
We report a case of rhabdomyolysis associated with Mycoplasma pneumoniae pneumonia in a 37-year-old Sri Lankan man who presented to the emergency department with complaints of feverishness, shortness of breath, cough, and generalised muscle pain. He had a serum creatinine kinase of 14 220 U/L, serum myoglobin of 1822 ng/mL, and serum creatinine of 195 µmol/L. His chest X-ray revealed bibasilar interstitial infiltrates. The antimycoplasma antibody titre was high. The patient was successfully treated with aggressive intravenous fluid replacement and azithromycin. The outcome was rapidly favourable, allowing us to discharge the patient 12 days after admission. On discharge, the serum creatinine kinase was 924 U/L and the creatinine was 126 µmol/L; the chest examination was unremarkable.
 
Key words: Mycoplasma pneumoniae; Pneumonia, mycoplasma; Rhabdom
 
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A pale Chinese boy with recurrent painful digital swelling

ABSTRACT

Hong Kong Med J 2012;18:163-5 | Number 2, April 2012
CASE REPORT
A pale Chinese boy with recurrent painful digital swelling
Frankie WT Cheng, WK Leung, Vincent Lee, Margaret HL Ng, Winnie CW Chu, KF Huen, MK Shing, CK Li
Department of Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong
 
 
Thalassaemia is the most common haemoglobinopathy in the Chinese population. However, recurrent painful digital swelling is not a typical manifestation of this well-known hereditary condition. We describe a case of co-inheritance of beta-thalassaemia and sickle cell trait in a Chinese family and a child who suffered from sickle cell/beta-thalassaemia with recurrent dactylitis. This report highlights awareness of this rare condition in the Chinese population, since acute manifestations can be life-threatening and mimic other emergency conditions. Prompt management can prevent further complications and avoid unnecessary interventions due to delay in diagnosis. A detailed family history and examination of the patient's peripheral blood smear is crucial to reach a correct diagnosis.
 
Key words: Anemia, sickle cell; beta-Thalassemia
 
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Acute torsion of a wandering spleen

ABSTRACT

Hong Kong Med J 2012;18:160-2 | Number 2, April 2012
CASE REPORT
Acute torsion of a wandering spleen
Y Lam, Kenny KY Yuen, LC Chong
Department of Surgery, United Christian Hospital, Kwun Tong, Hong Kong
 
 
The 'wandering spleen' is a rare condition due to extreme laxity or absence of ligaments that fix the organ in its normal anatomical position within the left upper quadrant. Without early surgical intervention, wandering spleen can lead to torsion and subsequent splenic infarction or rupture. Clinical suspicion plus urgent investigation and intervention are important, so as to salvage the spleen and prevent complications. We present a case of torsion of a wandering spleen in a 21-year-old young woman, who presented with a painful pelvic mass. We also reviewed the literature on this entity.
 
Key words: Pelvis; Spleen; Splenic diseases; Tomography, X-ray computed; Torsion; Wandering spleen
 
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Intrapleural injection of OK-432 as the primary in-utero treatment for fetal chylothorax

ABSTRACT

Hong Kong Med J 2012;18:156-9 | Number 2, April 2012
CASE REPORT
Intrapleural injection of OK-432 as the primary in-utero treatment for fetal chylothorax
Viola KT Leung, Stephen SH Suen, YH Ting, LW Law, TK Lau, TY Leung
Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong
 
 
Chylothorax is a rare congenital condition associated with significant perinatal mortality and morbidity. Previous treatments with repeated thoracocentesis or thoracoamniotic shunting were technically demanding, and associated with significant procedure-related complications and neonatal complications. Here we report the first successful case in Hong Kong treated by a simple and effective intervention, namely pleurodesis with OK-432, in a fetus presenting at 20 weeks of gestation with bilateral pleural effusion.
 
Key words: Chylothorax; Picibanil; Pleural effusion
 
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Benign metastasising leiomyoma after hysterectomy and bilateral salpingo-oophorectomy

ABSTRACT

Hong Kong Med J 2012;18:153-5 | Number 2, April 2012
CASE REPORT
Benign metastasising leiomyoma after hysterectomy and bilateral salpingo-oophorectomy
Manisha M Beck, Bivas Biswas, Aparajita D’Souza, Ramani Kumar
Christian Medical College and Hospital, Vellore, Tamil Nadu, India
 
 
Benign metastasising leiomyomatosis is a rare condition affecting women in the reproductive age-group with a history of uterine fibroids, who have undergone treatment by myomectomy or hysterectomy. It is characterised by development of multiple, indolent, smooth muscle tumours outside the uterus, most commonly in the lungs, and manifests several years after the uterine surgery. We describe the case of a young woman, who had undergone total abdominal hysterectomy and bilateral salpingo-oophorectomy for multiple fibroids and a right ovarian cyst. After 5 years of being on oestrogen replacement therapy, she was detected to have benign metastasising leiomyoma, for which an additional laparotomy was performed. At laparotomy, removal of the pelvic mass was associated with several complications. The metastatic lesions in the lung responded well to progestogens (megestrol acetate) alone as evidenced by regression of the lesions detected at follow-up after 6 months and 1 year.
 
Key words: Leiomyomatosis; Lung Neoplasms; Megestrol acetate; Progestins
 
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Cough mixture abuse and rhabdomyolysis

ABSTRACT

Hong Kong Med J 2012;18:68-9 | Number 1, February 2012
CASE REPORT
Cough mixture abuse and rhabdomyolysis
Jenny SK Tsang, WY Au
Department of Psychiatry, Kwai Chung Hospital, 3-15 Kwai Chung Hospital Road, Hong Kong
 
 
Cough mixture abuse is an emerging problem among young men in Oriental countries. Its metabolic consequences have been recognised only recently. Such abusers can develop severe folate deficiency, which may be related to peripheral and central nervous system defects. We report three cough mixture abusers with rhabdomyolysis. All suffered from folate deficiencies and also had a history of anti-psychotic drug use. This represents one more life-threatening side-effect from cough mixture abuse.
 
Key words: Antitussive agents; Cough/drug therapy; Folic acid deficiency; Rhabdomyolysis; Substance-related disorders
 
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Giant urethral diverticulum calculus presenting as scrotal abscess

ABSTRACT

Hong Kong Med J 2012;18:66-7 | Number 1, February 2012
CASE REPORT
Giant urethral diverticulum calculus presenting as scrotal abscess
KW Chan, WH Chu, IC Law
Department of Surgery, Kwong Wah Hospital, Yaumatei, Hong Kong
 
 
We report herein a patient with a urethral calculus associated with urethral diverticulum. A 39-year-old man presented with scrotal swelling and acute retention of urine. Computed tomography of the pelvis and cystoscopy demonstrated a giant calculus in the proximal penile urethra. Emergency in-situ lithotripsy was performed. Complete stone clearance was achieved and a large urethral diverticulum was encountered. The rare occurrence of urethral diverticulum and associated stone disease were discussed.
 
Key words: Diverticulum; Scrotum; Urethral diseases; Urinary bladder neck obstruction; Urinary calculi
 
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Acute ischaemic stroke during short-term travel to high altitude

ABSTRACT

Hong Kong Med J 2012;18:63-5 | Number 1, February 2012
CASE REPORT
Acute ischaemic stroke during short-term travel to high altitude
T Chan, Winnie WY Wong, Jonathan KC Chan, Johnny KF Ma, Henry KF Mak
Department of Diagnostic Radiology, The University of Hong Kong, Pokfulam, Hong Kong
 
 
This is a case report of a young healthy adult who had acute cerebral infarcts after a short-term visit to high-altitude area. He developed acute onset of right-sided limb weakness and right hemianopia a few hours after arrival at an altitude of 3600 m by train. He was initially treated for high-altitude cerebral oedema but later computed tomography and magnetic resonance imaging confirmed ischaemic infarcts in the medial left occipital lobe and left thalamus. Subsequent investigations, including laboratory tests and imaging including an echocardiogram, revealed no culpable predisposing factors.
 
Key words: Altitude sickness; Brain edema; Cerebral infarction; Magnetic resonance imaging; Tomography, X-ray computed
 
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Neonatal herpes: what lessons to learn

ABSTRACT

Hong Kong Med J 2012;18:60-2 | Number 1, February 2012
CASE REPORT
Neonatal herpes: what lessons to learn
KL Hon, TF Leung, HM Cheung, Paul KS Chan
Department of Paediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong
 
 
Vesicular rashes in neonates are challenging in terms of diagnosis and management. Herpes infection is an important diagnostic consideration. We report two illustrative neonatal cases of herpesvirus infections with vesicular rashes. Such babies may be remarkably asymptomatic. A high index of suspicion leading to a prompt diagnosis, timely quarantine measures, and institution of antiviral treatment are pivotal for desirable outcomes.
 
Key words: Herpes genitalis; Herpes simplex; Herpesvirus 2, human; Infant, newborns
 
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