OBJECTIVE. To assess the standard of hysterectomy in public hospitals in Hong Kong, so as to improve the quality of patient care and outcome.

DESIGN. Clinical audit.

SETTING. Twelve Hong Kong Hospital Authority public hospitals.

PATIENTS. All patients undergoing hysterectomy for benign gynaecological conditions during the period from 1 July 2002 to 31 December 2002 inclusive.

RESULTS. A total of 1330 patients were included for analysis: 934 (70.2%) having abdominal hysterectomies, 184 (13.8%) having laparoscopic hysterectomies, and 212 (15.9%) undergoing vaginal hysterectomies. Uterine fibroids constituted the commonest indication for abdominal (73.7%) and laparoscopic (61.4%) hysterectomies, while genital prolapse was the most common indication (96.2%) for vaginal hysterectomy. The majority of patients undergoing laparoscopic and vaginal hysterectomy (86.3% and 84.8% respectively) were given prophylactic antibiotics, in contrast to only 45.8% of those undergoing abdominal hysterectomy. In all, 85.8% of the abdominal and vaginal hysterectomies performed by trainees were supervised, while for trainees performing laparoscopic hysterectomy, all had specialists as their first assistant. The overall incidence of complications for vaginal hysterectomy was lower than that for both abdominal hysterectomy (P<0.001) and laparoscopic hysterectomy (P<0.05). Infectious morbidity was significantly higher in patients undergoing abdominal hysterectomy without prophylactic antibiotics.

CONCLUSION. The overall incidence of complications was lower for vaginal hysterectomies, as compared to both abdominal and laparoscopic hysterectomies, whereas the risk of urinary tract injury was significantly higher for laparoscopic hysterectomy. According to our audit, the level of supervision for the trainees was high. However, routine antibiotic prophylaxis should be more consistently used in the territory.

Key words: Audit; Hysterectomy

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OBJECTIVE. To study the tissue pathology of breast lesions associated with hydrophilic polyacrylamide gel injection augmentation mammoplasty.

DESIGN. Retrospective study.

SETTING. Private anatomical pathology practice, Hong Kong.

PATIENTS. Eight patients who underwent lumpectomy of the breast due to complications of hydrophilic polyacrylamide gel injection for augmentation mammoplasty.

MAIN OUTCOME MEASURES. Identification of hydrophilic polyacrylamide gel in breast tissue and associated pathological changes.

RESULTS. We reviewed the pathological changes in breast tissue associated with hydrophilic polyacrylamide gel injection in eight cases retrieved from our archive. Microscopically, the hydrophilic polyacrylamide gel appeared as pools of pale violet gelatinous material of variable size, between the interstices of connective tissue and fat cells. The larger pools were often surrounded by cellular reactions consisting of histiocytic cells and foreign body-type multinucleated giant cells. Inflammatory reaction featuring infiltration by lymphocytes and plasma cells in the adjacent breast tissue was observed in samples from four patients, and a sample from another patient showed acute inflammation with abscess formation. There was no evidence of abnormal cellular proliferation, atypia or malignant change in the stromal connective tissue or ductal-acinic epithelial components of the breast tissue.

CONCLUSIONS. Hydrophilic polyacrylamide gel injection for augmentation mammoplasty can give rise to a breast lump and inflammation. Pathologically, this complication is associated with fibrosis, foreign body reaction, and inflammation.

Key words: Acrylamides; Acrylic resins; Breast implants; Cosmetics; Injections

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OBJECTIVES. To compare the clinical characteristics of aortic dissection in Hong Kong with the International Registry of Aortic Dissection, and to evaluate the sensitivity of the Accident and Emergency Department in diagnosing aortic dissection and its role in aortic dissection management.

DESIGN. Retrospective observational study.

SETTING. Regional public hospital, Hong Kong.

PATIENTS. Newly diagnosed aortic dissection patients attending the Accident and Emergency Department from 2002 to 2005 inclusive.

MAIN OUTCOME MEASURES. Correct diagnosis in Accident and Emergency Department, tertiary unit transfer, and in-patient mortality.

RESULTS. Twenty-eight patients were found to have aortic dissection, with an estimated annual incidence of 2.1 per 100 000 inhabitants. The sensitivity of Accident and Emergency Department in diagnosing aortic dissection was 54%; 11% of the patients were diagnosed at postmortem examination. Compared to the International Registry of Aortic Dissection, the patients in this Tseung Kwan O Hospital study had less abrupt and less severe pain, less chest pain, and a lower proportion were operated on. Higher mortality was associated with age 70 years or older (odds ratio=6.4), female gender (21.0), known hypertension (3.8), systolic blood pressure below 100 mm Hg (6.0), aortic dissection not diagnosed in the Accident and Emergency Department (3.2), and the patient not reaching tertiary unit (33.8). The hourly cumulative mortality rate was 1.32%. The group of aortic dissections diagnosed in the Accident and Emergency Department had 55.1% more transfer to tertiary unit (95% confidence interval, 14.4-79.1%; P=0.006), 84.5 hours less transfer time (95.3-263.6 hours; P=0.232), and 27.2% lower mortality (12.6-58.6%; P=0.246). The yield rate of contrast computed tomography of thorax was 43%.

CONCLUSIONS. Diagnosing aortic dissection in the Accident and Emergency Department enabled optimal disposition and lower in-patient mortality.

Key words: Aneurysm, dissecting; Asian continental ancestry group; Emergency service, hospital; Tomography, spiral computed; Hospital mortality

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OBJECTIVE. To analyse the performance of opportunistic breast screening in local Well Women Clinics during the 5-year period from 1998 to 2002, with reference to international as well as our own earlier experience (1991 to 1993 to 1995).

DESIGN. Prospective study.

SETTING. Well Women Clinics in regional Hong Kong hospitals.

PARTICIPANTS. Women attending the Well Women Clinics of the Tung Wah Group of Hospitals for breast cancer screening.

MAIN OUTCOME MEASURES. All screening-detected breast cancers.

RESULTS. After 46 637 screening mammograms and excluding palpable masses detected by the patients themselves, 232 women were detected with cancers, yielding a crude detection rate of 5.0 per 1000. Age range for cancer detection was 35 to 72 (median, 49) years. Clinic staff detected palpable lumps in 83 patients, constituting 36% of the detected cancers, of which 15 (6.5% of all detected cancers) were not identified by mammography. The cancer detection rate was 5.9 per 1000 in the age-group 40-49 years and 3.7 per 1000 in those 50 years or older. The cancer detection rate was 58.5 per 1000 in the high-risk group (aged <40 years with positive family history). The minimal cancer detection rate was 2.2 per 1000, representing 45% of all cancers whose pathology was available to us. Ductal carcinoma in situ comprised 28% of all such cancers. Our recall rates were 4.6% for additional views only, 3.3% for ultrasound only, and 2.3% for both. Positive predictive values for abnormal mammograms and biopsies were 4.9% and 26.0%, respectively.

CONCLUSION. Mammographic screening has been reported to reduce mortality up to 35% in western countries. However, data concerning Asian Chinese populations are meagre. Our Well Women Clinics pioneered large-scale self-referred breast screening in Hong Kong. Despite the lower incidence of breast cancers than in Occidental populations, our screening programme performed comparably to those in the West, and has improved over time. Our screening service for self-referred women detected breast cancers even at an early stage, which facilitated a better prognosis and more treatment options, whilst appearing to be highly acceptable to our community. Besides, it could provide training and expertise in breast radiology and mammography, which are essential prerequisites for establishing population screening.

Key words: Mammography; Ultrasonography, mammary

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OBJECTIVES. To determine the outcomes after first-ever stroke, including mortality, dependence, and recurrence.

DESIGN. Retrospective study on a prospectively collected cohort.

SETTING. Regional hospital, Hong Kong.

PATIENTS. A cohort of 755 patients presented to our hospital from 1996 to 1998 with their first-ever stroke.

MAIN OUTCOME MEASURES. Mortality and stroke recurrence rate at 30 days, 1 year, and 5 years from the onset of the stroke. Dependence in activity of daily living at 5 years from the onset of stroke.

RESULTS. The mortality rate was 15.1% at 30 days, 22.5% at 1 year, and 39.7% at 5 years from the onset of the first-ever stroke. The rate of stroke recurrence was 0.9% at 30 days, 7.0% at 1 year, and 21.2% at 5 years from the onset of first-ever stroke. Among patients presenting with ischaemic strokes, 109 (20.6%) had a recurrence, of which 92 (84%) were ischaemic strokes and 17 (16%) were haemorrhagic. Among patients presenting with intracerebral haemorrhage, 25 (23.1%) had a recurrence, of which 12 (48%) were haemorrhagic strokes and 13 (52%) patients were ischaemic. After 5 years, 11% of the patients were dependent in terms of activity of daily living.

CONCLUSIONS. The long-term prognosis after first-ever stroke is poor—5 years after their stroke, 39.7% of patients had died and 10.7% were dependent in terms of activity of daily living; 136 (21%) who survived at least 30 days after the initial stroke, had a recurrence within 5 years.

Key words: Cerebrovascular accident; Ischemic attack, transient; Prognosis; Recurrence; Treatment outcome

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