Pulmonary embolism presenting as disseminated intravascular coagulation

ABSTRACT

Hong Kong Med J 2002;8:142-3 | Number 2, April 2002
CASE REPORT
Pulmonary embolism presenting as disseminated intravascular coagulation
SSL Choi, SY Pang, WP Mak, A KO
Department of Medicine and Geriatrics, Caritas Medical Centre, 111 Wing Hong Street, Shamshuipo, Kowloon, Hong Kong
 
 
We report an unusual case of disseminated intravascular coagulation. Occult pulmonary embolism is a recognised cause of disseminated intravascular coagulation. Unexplained shock should prompt the physician to search for a thrombotic cause such as pulmonary thromboembolism.
 
Key words: Disseminated intravascular coagulation; Pulmonary embolism
 
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Respiratory insufficiency in a Chinese adult with mitochondrial myopathy

ABSTRACT

Hong Kong Med J 2002;8:137-40 | Number 2, April 2002
CASE REPORT
Respiratory insufficiency in a Chinese adult with mitochondrial myopathy
KC Chang, YF Mak, WC Yu, KK Lau, WW Yan, TC Chow
Yaumatei Chest Clinic, Yaumatei Jockey Club Polyclinic, 145 Battery Street, Kowloon, Hong Kong
 
 
Mitochondrial myopathy is an important but uncommon cause of respiratory insufficiency in adults. We report the first case of respiratory insufficiency associated with adult-onset mitochondrial myopathy seen in a Chinese adult in Hong Kong. The patient presented with peripheral oedema and shortness of breath over 2 to 3 days. There was a history of gradual progressive limb weakness over approximately 2 years, hypertrophic cardiomyopathy, intermittent diarrhoea, and weight loss. The diagnosis was made by skeletal muscle biopsy and molecular study, which revealed the A3243G point mutation.
 
Key words: MELAS syndrome; Mitochondrial myopathies; Myocardial diseases; Respiratory insufficiency
 
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Three patients with lead poisoning following use of a Chinese herbal pill

ABSTRACT

Hong Kong Med J 2002;8:60-2 | Number 1, February 2002
CASE REPORT
Three patients with lead poisoning following use of a Chinese herbal pill
TW Auyeung, KKF Chang, CH To, A Mak, ML Szeto
Department of Medicine and Geriatrics, Tuen Mun Hospital, Tsing Chung Koon Road, Tuen Mun, Hong Kong
 
 
We report on three patients with lead poisoning following use of the Chinese herbal pill Bao ning dan, prepared by the same traditional Chinese medicine practitioner. The patients had varying degrees of exposure to Bao ning dan and different clinical manifestations. Blood lead concentrations did not correlate with clinical severity. Two patients received chelating therapy and blood lead concentrations subsequently rapidly decreased. One patient was managed conservatively and end-organ complications resolved gradually. With increasing use of traditional Chinese medicines, related adverse reactions are expected to become increasingly common. Practitioners of western medicine should remain alert to this possibility. A comprehensive drug review, including the use of herbal medicines, should form a routine part of medical history taking.
 
Key words: Drugs, Chinese herbal; Lead poisoning; Medicine, Chinese traditional
 
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Prolonged jaundice following percutaneous coronary intervention and ticlopidine therapy

ABSTRACT

Hong Kong Med J 2002;8:57-9 | Number 1, February 2002
CASE REPORT
Prolonged jaundice following percutaneous coronary intervention and ticlopidine therapy
PT Tsui, ST Lai, WS Leung, NS Mok, CW Wu, ST Lau, YC Choi
Department of Medicine and Geriatrics, Princess Margaret Hospital, 2-10 Princess Margaret Hospital Road, Laichikok, Hong Kong
 
 
Ticlopidine, an adenosine diphosphate receptor blocker, is widely used to prevent subacute stent thrombosis after percutaneous coronary intervention. Along with neutropenia and thrombotic thrombocytopenic purpura, cholestatic hepatitis is one of the most serious potential side-effects of ticlopidine therapy. Four patients with prolonged jaundice after ticlopidine therapy, including one fatal case, are presented. Alternative antithrombotic therapy for subsequent percutaneous coronary intervention is also described. Clopidogrel therapy was found to be safe and effective in two patients with a history of ticlopidine-related cholestatic hepatitis.
 
Key words: Angioplasty; Cholestasis; Jaundice; Liver/pathology; Ticlopidine/adverse effects
 
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Brain tuberculoma in Hong Kong

ABSTRACT

Hong Kong Med J 2002;8:52-6 | Number 1, February 2002
CASE REPORT
Brain tuberculoma in Hong Kong
WY Lee, KY Pang, CK Wong
Department of Neurosurgery, Pamela Youde Nethersole Eastern Hospital, 3 Lok Man Road, Chai Wan, Hong Kong
 
 
We report two cases of brain tuberculoma occurring in patients residing in Hong Kong. Both patients presented with headache and had space-occupying lesions evident on computed tomography scans of the brain. The patients had no history of tuberculosis and no symptoms of concurrent extracranial tuberculosis were evident. The diagnosis of tuberculoma was made at the time of surgical excision. Delayed diagnosis of brain tuberculoma is likely to occur in industrialised countries where tuberculosis is rare. In Hong Kong, however, with a constant influx of foreign domestic workers from endemic regions, a high index of suspicion should be maintained. Imaging studies support, but do not confirm, the diagnosis of brain tuberculoma. We recommend obtaining a definitive histological diagnosis, with computed tomography–guided stereotactic biopsy, before starting antituberculous therapy. Surgical excision is necessary in patients with raised intracranial pressure secondary to the lesion, who are not responding to medical therapy.
 
Key words: Diagnosis, differential; Hong Kong; Magnetic resonance imaging; Tomography, X-ray computed; Tuberculoma, intracranian
 
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Hepatocellular carcinoma with metastasis to the skull base, pituitary gland, sphenoid sinus, and cavernous sinus

ABSTRACT

Hong Kong Med J 2002;8:48-51 | Number 1, February 2002
CASE REPORT
Hepatocellular carcinoma with metastasis to the skull base, pituitary gland, sphenoid sinus, and cavernous sinus
TH Aung, YC Po, WK Wong
Department of Neurosurgery, Princess Margaret Hospital, 2-10 Princess Margaret Hospital Road, Kowloon, Hong Kong
 
 
Two cases of hepatocellular carcinoma, with metastases to the skull base, pituitary gland, sphenoid sinus, and cavernous sinus are reported. Patients presented with diplopia, retro-orbital headache, and multiple cranial nerves palsies. Pituitary metastases may require surgery as palliative treatment, and for the confirmation of histology. One of the current cases was diagnosed with hepatocellular carcinoma prior to transphenoidal resection of the pituitary metastasis. The second patient was found to have hepatocellular carcinoma after review of histology, and the development of signs and symptoms relating to the primary tumour.
 
Key words: Carcinoma, hepatocellular; Cavernous sinus; Pituitary gland; Sphenoid sinus
 
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Severe cow's milk protein allergy in a Chinese neonate

ABSTRACT

Hong Kong Med J 2001;7:442-4 | Number 4, December 2001
CASE REPORT
Severe cow's milk protein allergy in a Chinese neonate
LY Siu, K Tse, YS Lui
Paediatric Department, Tuen Mun Hospital, Tsing Chung Koon Road, Tuen Mun, Hong Kong
 
 
Cow's milk protein allergy is a growing problem in developed countries. We report the case of a Chinese infant, born at term, who presented on day 28 with severe growth failure, chronic diarrhoea, and metabolic acidosis. Investigations supported a diagnosis of cow's milk protein allergy. This was confirmed by withdrawing and reintroducing the relevant infant formula under controlled clinical conditions. Both acidosis and diarrhoea were seen to resolve, and 'catch-up' growth was evident after introduction of an elemental infant formula. Early recognition of this problem leads to a rapid 'cure', as seen in this case. However, later presentation with other atopic conditions has been reported.
 
Key words: Food hypersensitivity; Milk hypersensitivity
 
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Diagnosis and current management of gastrojejunocolic fistula

ABSTRACT

Hong Kong Med J 2001;7:439-41 | Number 4, December 2001
CASE REPORT
Diagnosis and current management of gastrojejunocolic fistula
DPC Chung, RSK Li, HT Leong
Department of Surgery, Alice Ho Miu Ling Nethersole Hospital, 11 Chuen On Road, Tai Po, Hong Kong
 
 
Gastrojejunocolic fistula is a late complication of gastroenterostomy and is associated with inadequate gastric resection and incomplete vagotomy. In the past, attempted primary repair had high mortality and staged operations were normally performed. We present two cases of gastrojejunocolic fistula and discuss the modern management of this condition. In both cases, improved nutritional support allowed successful one-stage surgical repair to be performed.
 
Key words: Gastrectomy; Gastric fistula; Gastroscopy; Intestinal fistula
 
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The monoplace hyperbaric chamber and management of decompression illness

ABSTRACT

Hong Kong Med J 2001;7:435-8 | Number 4, December 2001
CASE REPORT
The monoplace hyperbaric chamber and management of decompression illness
RCT Li
Asia Hyperbaric Center, AML, 28A Shum Wan Road, Wong Chuk Hang, Hong Kong
 
 
Three cases of decompression illness are reported. Two patients presented with joint pain and skin signs, while one patient presented with joint pain and neurological signs and symptoms. The patients received emergency recompression therapy in a Hong Kong clinic, using a monoplace hyperbaric chamber. All three patients were treated successfully and no residual signs or symptoms were evident on review at 90 days' post-treatment. Issues concerning the use of monoplace and multiplace hyperbaric chambers are also discussed, along with additional clinical applications of the monoplace hyperbaric chamber.
 
Key words: Decompression sickness; Diving; Emergency treatment; Hyperbaric oxygenation
 
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Isolated foetal ascites

ABSTRACT

Hong Kong Med J 2001;7:432-4 | Number 4, December 2001
CASE REPORT
Isolated foetal ascites
WC Leung, YH Lam, MHY Tang
Department of Obstetrics and Gynaecology, The University of Hong Kong, Tsan Yuk Hospital, Sai Ying Pun, Hong Kong
 
 
The prenatal diagnosis and perinatal outcome of two patients with isolated foetal ascites compatible with chyloperitoneum is described. The foetal ascites resolved spontaneously after delivery with good perinatal outcome in both cases. A good prognosis can be anticipated in such cases. Antepartum and intrapartum interventions are seldom necessary.
 
Key words: Ascites; Chyloperitoneum; Fetal diseases; Prenatal diagnosis
 
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