Chronic bullous dermatosis in Hong Kong

ABSTRACT

Hong Kong Med J 1996;2:366-72 | Number 4, December 1996
ORIGINAL ARTICLE
Chronic bullous dermatosis in Hong Kong
RCW Su, LY Chong
Social Hygiene Services (Dermatology), Department of Health, Hong Kong
 
 
The medical records of patients with chronic bullous dermatosis who have attended the Social Hygiene Service in Hong Kong were reviewed retrospectively. All skin biopsy reports in the Social Hygiene Service (Dermatology) for patients with a diagnosis of vesiculo-bullous disease were retrieved along with the respective medical records for the period from January 1985 through December 1992. The epidemiology, treatment, course, and prognostic data were reviewed. Of 234 patients with chronic bullous disease, the three most common diagnoses were bullous pemphigoid (n=149, 63.7%), pemphigus vulgaris (n=38, 16.2%), and pemphigus foliaceus (n=23, 9.9%). Only six patients (2.6%) had dermatitis herpetiformis, and another six had linear immunoglobulin A disease (2.6%). Systemic steroids (40-80 mg/day) were the mainstay of therapy for pemphigus and pemphigoid patients. The most common steroid-sparing agent employed was azathioprine. Dapsone was the treatment of choice for dermatitis herpetiformis and gluten-free diet was not employed for control of the skin condition in these patients.
 
Key words: Pemphigoid, bullous; Skin diseases, vesiculobullous; Autoimmune diseases; Hong Kong
 
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Characteristics of the Baumann's angle in Hong Kong Chinese children

ABSTRACT

Hong Kong Med J 1996;2:363-5 | Number 4, December 1996
ORIGINAL ARTICLE
Characteristics of the Baumann's angle in Hong Kong Chinese children
PPS Ko, JKY Ng, JJ Lam, HM Ho, CY Lam, SH Yeung
Department of Orthopaedics and Traumatology, Pamela Youde Nethersole Eastern Hospital, 3 Lok Man Road, Chai Wan, Hong Kong
 
 
This study defined the characteristics of Baumann's angle in a local population. One hundred and sixty-eight radiographs were studied and categorised into age groups at two-year intervals. Two observers measured all the angles and the data was analysed by computer using various statistical methods. The mean value was 70.1? in boys and 69.9? in girls; no statistically significant difference could be demonstrated in the different sex or age groups. However, some differences to Western studies were noted. This could be important information for the management of supracondylar fractures of the elbow in children.
 
Key words: Humeral fractures; Elbow
 
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A survey of hospital readmission in elderly patients

ABSTRACT

Hong Kong Med J 1996;2:258-62 | Number 3, September 1996
ORIGINAL ARTICLE
A survey of hospital readmission in elderly patients
CF Ko, TKK Yu, TPS Ko
Department of Geriatrics, Princess Margaret Hospital, Lai Chi Kok, Kowloon, Hong Kong
 
 
This survey was designed to study the problem of hospital readmission in a geriatric centre in Hong Kong. A retrospective survey of 565 unplanned admissions to a geriatric department showed that the rate of unplanned readmission was 25.3%. Only 56.7% of the selected hospital records could be retrieved for further analysis. Of the unplanned readmissions, 19% were potentially avoidable. The reasons for readmission included medication problems (2.5%), inadequate medical management (16.5%), natural clinical course (32.9%), and new clinical problem (48.1%). A statistical difference was found in the readmission rates for those patients with or without multiple admissions in the previous year (P = 0.001). Those patients who presented with cardiovascular problems were also more likely to be readmitted, although this difference was not statistically significant.
 
Key words: Patient readmission; Aged; Geriatrics
 
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Assisted reproduction in Hong Kong: status in the 1990s

ABSTRACT

Hong Kong Med J 1996;2:253-6 | Number 3, September 1996
ORIGINAL ARTICLE
Assisted reproduction in Hong Kong: status in the 1990s
Hong Kong IVF Study Group
 
 
Information on assisted reproduction in Hong Kong for the period from January 1992 to December 1993 was collected from the three centres that offer assisted reproduction. Altogether, 912 treatment cycles of in vitro fertilisation and embryo transfer, 158 treatment cycles of gamete intrafallopian transfer, and 87 cycles of zygote intrafallopian transfer were initiated during this period. The delivery rates per cycle started were 8.4% for in vitro fertilisation, 29.1% for gamete intrafallopian transfer, and 13.8% for zygote intrafallopian transfer. During the same period, 233 cycles of replacement of frozen thawed embryos were completed with a delivery rate of 11.2% per cycle. Pregnancies were also achieved using oocyte donation and micromanipulation techniques.
 
Key words: Reproduction techniques; Fertility agents, female; Fertilizaton in vitro; Fertilization, delayed
 
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Experience with a new cervical smear sampling device

ABSTRACT

Hong Kong Med J 1996;2:248-52 | Number 3, September 1996
ORIGINAL ARTICLE
Experience with a new cervical smear sampling device
AR Chang
Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong
 
 
The cervical smear is effective in detecting the precursor lesions of cervical cancer. With appropriate treatment invasive carcinoma may be prevented. For a smear to have maximum diagnostic value, it must contain sufficient numbers of well-preserved cells from the transformation zone of the cervix where most malignancies develop. A major cause of a non-diagnostic smear is poor sampling. A new sampling device, the Cervex-Brush, has been touted as being capable of producing a superior specimen compared with the modified Ayre's spatula, which is the most widely used cervical sampler in Hong Kong. When evaluated on 500 women presenting for a smear at a community cervical screening clinic, the Cervex-Brush was found to produce a good quality sample as judged by the presence of endocervical and/or metaplastic cells, lack of blood, and the thickness of the cell sample. In the drive to ensure that cervical smears are of the highest quality, the Cervex-Brush is worthy of further evaluation for routine use. Although it is significantly more expensive, the extra costs could be offset by the substantial savings that can accrue from having a smaller number of substandard samples and the need to repeat smears.
 
Key words: Cervical smear; Cervical intraepithelial neoplasia; Cytodiagnosis
 
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Discoid lupus erythematosus in Hong Kong Chinese: a review of 12 cases

ABSTRACT

Hong Kong Med J 1996;2:239-46 | Number 3, September 1996
ORIGINAL ARTICLE
Discoid lupus erythematosus in Hong Kong Chinese: a review of 12 cases
WYM Tang, LY Chan, KK Lo
Social Hygiene Service, Department of Health, Hong Kong Government, Hong Kong
 
 
The records of twelve patients with discoid lupus erythematosus who attended the Social Hygiene Service, of the Department of Health, Hong Kong, during the period rom March 1987 through June 1994 were reviewed and analysed. Our series shows that discoid lupus erythematosus affects both men and women equally. Compared with studies in Caucasians, a higher proportion of our patients (17%) subsequently developed features that satisfied the American College of Rheumatology's revised classification criteria for systemic lupus erythematosus. Hence, regular follow up of these patients for the early detection of systemic lupus erythematosus is important.
 
Key words: Lupus erythematosus, discoid; Lupus erythematosus, systemic; Hong Kong; Chloroquine
 
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Outcomes of elderly patients categorised as "do not resuscitate"

ABSTRACT

Hong Kong Med J 1996;2:146-52 | Number 2, June 1996
ORIGINAL ARTICLE
Outcomes of elderly patients categorised as "do not resuscitate"
PS Ip, CM Lum, E Hui, KH Or, J Woo
Medical & Geriatric Unit, Shatin Hospital, Shatin, Hong Kong
 
 
In this clinical audit, we compared the guidelines on cardiopulmonary resuscitation in our hospital with those from the Royal College of Physicians (London). Forty-six of 72 cases designated as "do not resuscitate" at the Prince of Wales Hospital and transferred to Shatin Hospital were re-categorised to receive active resuscitation. Documentation and the reasons for the "do not resuscitate" order were not made in fewer than 7% of patients. The decision was made with patients/carers in 61% of patients designated "do not resuscitate" at Shatin Hospital. Of those 72 patients, 68% were eventually discharged and only 16% died in the subsequent nine months. Among those discharged, functional levels were not worse compared with their premorbid state. Hence, our policy has not led to undue prolongation of life and disability with poor quality of life. We recommend more training in patient communication skills and studies on attitudes of patients towards the decision not to resuscitate.
 
Key words: Aged; Resuscitation orders; Disabled; Quality of life
 
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Features of head injury at Prince of Wales Hospital, Hong Kong, from 1989 to 1993

ABSTRACT

Hong Kong Med J 1996;2:141-5 | Number 2, June 1996
ORIGINAL ARTICLE
Features of head injury at Prince of Wales Hospital, Hong Kong, from 1989 to 1993
JNK Hsiang, TKW Cheung, KYC Goh, JMK Lam, X-L Zhu, WS Poon
Neurosugical Unit, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong
 
 
The features of head injury at Prince of Wales Hospital, Hong Kong, were determined by reviewing the medical records of head-injured patients admitted to its neurosurgical service during the period commencing January 1989 to December 1993. During this time, there was a decline in the total number of head injury admissions. This reduction was secondary to a decrease in admissions for minor head injuries. The number of severe head injuries remained constant during these years. Falls represented the leading cause of head injury and accounted for more than 50% of all head injury admissions. Fall from a height was mainly a paediatric problem and falling at ground level was most common in the elderly. In teenagers and young adults, the most common causes of head injury were bicycle- and traffic-related accidents. Traffic-related accidents accounted for more than 50% of all head injury fatalities. There was a direct relationship between age and the mortality rate.
 
Key words: Epidemiology, head injury; Head injuries; Mortality, head injury
 
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Immune response to hepatitis B vaccine in health care workers in Hong Kong

ABSTRACT

Hong Kong Med J 1996;2:138-40 | Number 2, June 1996
ORIGINAL ARTICLE
Immune response to hepatitis B vaccine in health care workers in Hong Kong
WL Lim, DA Wong, KC Cheng
Government Virus Unit, Department of Health, Queen Mary Hospital, Pokfulam, Hong Kong
 
 
The hepatitis B virus is hyperendemic in Hong Kong. Health care workers are at increased risk of acquiring hepatitis B because of frequent exposure and are therefore advised to receive hepatitis B vaccination. Immune response rates among 1102 female and 567 male health care workers in Hong Kongwere examined and analysed. There was a good overall response rate of 93.8%, with women responding better than men. Among female health care workers, the proportion with an inadequate antibody response increased from 3.5% in those younger than 35 years old to 6.5% in those aged 35 years and older. Post-vaccination testing should be recommended to identify non-responders and to guide post-exposure management.
 
Key words: Hepatitis B virus; Hepatitis B vaccines; Immunity, active
 
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The pathology of bone marrow transplantation in Hong Kong Chinese

ABSTRACT

Hong Kong Med J 1996;2:133-7 | Number 2, June 1996
ORIGINAL ARTICLE
The pathology of bone marrow transplantation in Hong Kong Chinese
TWH Shek, IOL Ng, EKW Chiu, KW Chan
Department of Pathology, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong
 
 
The pathological lesions found in 68 successfully engrafted patients with human leucocyte antigen-matched sibling-related bone marrow transplants werereviewed retrospectively. Twenty-six (38%) patients had acute graft-versus-host disease, which was slightly less than that reported in Caucasians. Skin was a constant site of involvement (100%), followed by the gastrointestinal tract (74%) and liver (59%). There was a 74% correlation between the clinical and histological grading of cutaneous graft-versus-host disease, while that of the gastrointestinal tract was lower at 60%. Cytomegalovirus colitis was found on histological examination of two patients clinically thought to have graft-versus-host disease. Histological evidence of infection, which included viral hepatitis (n=5), disseminated cytomegalovirus infection (n=3), disseminated aspergillosis (n=2), systemic candidiasis (n=2), Pneumocystis carinii pneumonia (n=1), and bacterial pneumonia (n=1), was present in 14 patients. In addition to graft-versus-host disease and infections, there was a case of veno-occlusive disease of the liver. Histological examination is important in distinguishing graft-versus-host disease from infection and other complications in bone marrow transplantation.
 
Key words: Bone marrow transplantation; Pathology; Graft vs host disease; Opportunistic infections; Immunosuppression
 
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