Lower extremity amputation in Hong Kong

ABSTRACT

Hong Kong Med J 2005;11:147-52 | Number 3, June 2005
ORIGINAL ARTICLE
Lower extremity amputation in Hong Kong
MWN Wong
Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong
 
 
OBJECTIVE. To evaluate the characteristics and outcome of patients undergoing lower extremity amputation in Hong Kong.
 
DESIGN. Cohort study.
 
SETTING. University teaching hospital, Hong Kong.
 
PARTICIPANTS. One hundred and eighty-four Chinese adults who underwent lower extremity amputation.
 
MAIN OUTCOME MEASURES. Demographic data of the cohort, wound complication and revision amputation rates, prosthesis use, functional ambulation level and institutionalisation at postoperative 6 months, operative mortality, and long-term survival.
 
RESULTS. The majority of patients (83.1%) who underwent lower extremity amputation were aged over 60 years. Vascular occlusive disease was the most common underlying pathology, followed by infection. The wound complication and operative mortality rates were high. Only 43.0% of patients were able to resume community ambulation at 6 months and 40.7% became institutionalised. After high-level amputations, 22.3% managed to use a prosthesis. The median survival after lower extremity amputation was 1008 days. High-level amputation was associated with lower wound complication and revision amputation rates, but an inferior functional outcome and survival compared with foot amputation.
 
CONCLUSIONS. Lower extremity amputation is associated with high morbidity and mortality, especially with high-level amputations. It places a heavy burden of care on patients, their families, the health care system, and society. Appropriate health care planning, provisions, and coordinated efforts at various levels are necessary to improve the situation. Major efforts must also be focused on preventing vascular occlusive disease and diabetes.
 
Key words: Amputation; Chinese; Mortality; Treatment outcome
 
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Arthroscopic procedures for the treatment of anterior shoulder instability: local experiences

ABSTRACT

Hong Kong Med J 2005;11:104-9 | Number 2, April 2005
ORIGINAL ARTICLE
Arthroscopic procedures for the treatment of anterior shoulder instability: local experiences
ST Choi, PYT Tse
Department of Orthopaedics and Traumatology, Kwong Wah Hospital, 25 Waterloo Road, Kowloon, Hong Kong
 
 
OBJECTIVE. To review the outcomes of arthroscopic stabilisation procedures for the treatment of recurrent anterior shoulder dislocation.
 
DESIGN. Retrospective study.
 
SETTING. Regional hospital, Hong Kong.
 
PATIENTS. Patients receiving arthroscopic stabilisation procedures for recurrent anterior shoulder dislocation between 1999 and 2003.
 
MAIN OUTCOME MEASURES. Functional outcomes including pain, range of motion, and activity level were assessed using the Constant score. Intra-operative findings were also discussed.
 
RESULTS. A total of 18 arthroscopic stabilisation procedures were performed for the treatment of recurrent shoulder instability. Two cases converted to open procedures were excluded from this review. The overall outcomes were good and seven patients reported a full recovery. Fourteen out of 16 patients reported minimal or no pain, and the mean Constant score was 80. There were no cases of re-dislocation and no major complication was noted.
 
CONCLUSION. All the reviewed patients had a satisfactory functional recovery. Therefore, we believe that the use of arthroscopic stabilisation procedure can produce a favourable outcome for appropriate shoulder pathologies.
 
Key words: Arthroscopy; Joint instability; Recurrence; Shoulder dislocation
 
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Assessment of the Pediatric Index of Mortality (PIM) and the Pediatric Risk of Mortality (PRISM) III score for prediction of mortality in a paediatric intensive care unit in Hong Kong

ABSTRACT

Hong Kong Med J 2005;11:97-103 | Number 2, April 2005
ORIGINAL ARTICLE
Assessment of the Pediatric Index of Mortality (PIM) and the Pediatric Risk of Mortality (PRISM) III score for prediction of mortality in a paediatric intensive care unit in Hong Kong
KMS Choi, DKK Ng, SF Wong, KL Kwok, PY Chow, CH Chan, JCS Ho
Department of Paediatrics, Kwong Wah Hospital, 25 Waterloo Road, Hong Kong
 
 
OBJECTIVE. To compare two models (The Pediatric Risk of Mortality III score and Pediatric Index of Mortality) for prediction of mortality in a paediatric intensive care unit in Hong Kong.
 
DESIGN. Prospective case series.
 
SETTING. A five-bed paediatric intensive care unit in a general hospital in Hong Kong.
 
PATIENTS. All patients consecutively admitted to the unit between April 2001 and March 2003.
 
MAIN OUTCOME MEASURES. Scores for both models compared with observed mortality.
 
RESULTS. A total of 303 patients were admitted to the paediatric intensive care unit during the study period. The median age was 2 years, with an interquartile range of 7 months to 7 years. The male to female ratio was 169:134 (55.8%:44.2%). The median length of hospital stay was 3 days. The overall predicted number of deaths using The Pediatric Risk of Mortality III score was 10.2 patients whereas that by Pediatric Index of Mortality was 13.2 patients. The observed mortality was eight patients. The area under the receiver operating characteristics curve for the two models was 0.910 and 0.912, respectively.
 
CONCLUSION. The predicted mortality using both prediction models correlated well with the observed mortality.
 
Key words: Child; Intensive care units, pediatric; Mortality; Predictive value of tests; Severity of illness index
 
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Primary immunodeficiency in Hong Kong and the use of genetic analysis for diagnosis

ABSTRACT

Hong Kong Med J 2005;11:90-6 | Number 2, April 2005
ORIGINAL ARTICLE
Primary immunodeficiency in Hong Kong and the use of genetic analysis for diagnosis
DST Lam, TL Lee, KW Chan, HK Ho, YL Lau
Department of Paediatrics and Adolescent Medicine, University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Hong Kong
 
 
OBJECTIVES. To review the management of primary immunodeficiency and discuss recent advances in genetic analysis.
 
DESIGN. Retrospective study.
 
SETTING. University teaching hospital, Hong Kong.
 
PATIENTS. Children diagnosed with primary immunodeficiency and followed up in the immunology clinic during the period 1988 to 2003.
 
MAIN OUTCOME MEASURES. Demographic data, co-morbidities and treatment of patients, outcome and complications; identification of disease by genetic mutations.
 
RESULTS. Medical records of a total of 117 patients (72 male, 45 female) diagnosed with primary immunodeficiency in the Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, Hong Kong during the past 15 years (1988-2003) were reviewed. All patients were followed up in the immunology clinic. Some patients had been referred from the private sector or other hospitals for immunological workup. Six categories of primary immunodeficiency were identified: predominantly humoral defect (n=50), predominantly cellular defect (n=22), combined humoral and cellular defect (n=5), phagocytic defect (n=18), complement disorders (n=4), and others (n=18). Although infection was the underlying cause of most co-morbidities and mortality, autoimmune (n=7) and allergic (n=23) manifestations were common. In addition, three patients developed lymphoma. Recent advances in the genetic diagnosis of several types of primary immunodeficiency were also reviewed: X-linked Wiskott-Aldrich syndrome, X-linked chronic granulomatous disease, X-linked agammaglobulinaemia, X-linked lymphoproliferative syndrome, leukocyte adhesion disease type I, and X-linked hyperimmunoglobulin M syndrome. This provides an invaluable means of understanding the molecular basis of primary immunodeficiency and has important clinical applications.
 
CONCLUSIONS. Co-morbidities like autoimmune disease and allergic disease are common in patients with primary immunodeficiency and should be carefully evaluated. Likewise, a diagnosis of primary immunodeficiency should be considered when evaluating patients with these conditions. Rapid progress in the field of molecular genetics will enable definite and early diagnosis, and more importantly, potential curative therapy to be administered.
 
Key words: Allergy and immunology; Autoimmune diseases; Genetic diseases, X-linked; Immunologic deficiency syndromes
 
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Causes of childhood blindness in a school for the visually impaired in Hong Kong

ABSTRACT

Hong Kong Med J 2005;11:85-9 | Number 2, April 2005
ORIGINAL ARTICLE
Causes of childhood blindness in a school for the visually impaired in Hong Kong
DSP Fan, TYY Lai, EYY Cheung, DSC Lam
Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Eye Hospital, 147K Argyle Street, Hong Kong
 
 
OBJECTIVE. To identify the causes of blindness in children attending a school for the blind in Hong Kong.
 
DESIGN. Cross-sectional observational study.
 
SETTING. School for blind children in Hong Kong.
 
PARTICIPANTS. Eighty-two blind students at the Ebenezer School and Home for the Visually Impaired were examined between December 1998 and August 1999.
 
MAIN OUTCOME MEASURES. Demographic data were obtained from students and a questionnaire assessment made of their medical and ocular history. Visual acuity was assessed and visual loss classified according to the World Health Organization classification of visual impairment. Complete ophthalmic assessments were performed in all students including slit-lamp examination and dilated binocular indirect ophthalmoscopy.
 
RESULTS. The mean age of the students was 12.2 years. Ten (12.2%) had a family history of eye disease. Major past medical illnesses were reported in 50% with prematurity and diseases of the central nervous system found in 26.8% and 11.0% of students, respectively. The most common anatomical site for visual impairment was the retina (47.6%), followed by diseases of the optic nerve (14.6%), and diseases of the anterior segment and the lens (14.6%).
 
CONCLUSIONS. The pattern of childhood blindness in Hong Kong is similar to that seen in other developed countries. Preventable causes of childhood blindness, such as prematurity and birth asphyxia, were responsible for a large proportion of cases. Early diagnosis and treatment of such conditions may reduce the incidence of childhood blindness in Hong Kong.
 
Key words: Blindness; Cataract; Child; Optic nerve diseases; Retinopathy of prematurity
 
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Surgical intervention for benign prostatic hyperplasia in Hong Kong

ABSTRACT

Hong Kong Med J 2005;11:79-84 | Number 2, April 2005
ORIGINAL ARTICLE
Surgical intervention for benign prostatic hyperplasia in Hong Kong
WH Sun, CW Man, RLC Ngai, BTH Wong, TF Yiu
Urology Division, Department of Surgery, Alice Ho Miu Ling Nethersole Hospital and North District Hospital, Hong Kong
 
 
OBJECTIVES. To review the treatment of benign prostatic hyperplasia in Hong Kong.
 
DESIGN. Questionnaire study and review of previous presentations at the Hong Kong Urological Association meetings.
 
SETTING. Urology centres in the public sector, Hong Kong.
 
PARTICIPANTS. Thirteen public urology centres replied to the questionnaire survey. Thirty-two papers on benign prostatic hyperplasia presented at past annual scientific meetings of the Hong Kong Urological Association were identified. This would provide an overview of the development of surgical interventions for the treatment of benign prostatic hyperplasia carried out in Hong Kong.
 
RESULTS. Most known surgical techniques have been practised in Hong Kong. Many ‘minimally invasive procedures’ have now fallen out of favour. Some newer techniques are now available and have produced favourable results. Nonetheless, transurethral resection of the prostate remains the standard surgical intervention in 12 of 13 centres in Hong Kong.
 
CONCLUSION. Transurethral resection of the prostate remains the technique of choice for the treatment of benign prostatic hyperplasia in Hong Kong. New techniques should be comprehensively studied and evaluated before being introduced into regular practice.
 
Key words: Data collection; Prostatic hyperplasia; Surgery
 
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Characterising atherothrombosis in Hong Kong: results of the Hong Kong data from a global atherothrombosis epidemiological survey

ABSTRACT

Hong Kong Med J 2005;11:36-41 | Number 1, February 2005
ORIGINAL ARTICLE
Characterising atherothrombosis in Hong Kong: results of the Hong Kong data from a global atherothrombosis epidemiological survey
MW Tsang, CL Chu, YW Kam, KH Kwong, CK Lam, SY Ngan, YK Yu
Diabetes Ambulatory Care Centre, Department of Medicine and Geriatrics, United Christian Hospital, 130 Hip Wo Street, Kwun Tong, Hong Kong
 
 
OBJECTIVES. To describe the characteristics of patients in Hong Kong with or at risk of atherothrombosis, to determine the proportion of symptomatic patients with more than one vascular bed affected, and to assess the relationship between ankle brachial index and disease severity.
 
DESIGN. Local participation in an international prevalence study.
 
SETTING. Five centres in Hong Kong.
 
PARTICIPANTS. A total of 210 subjects were recruited (105 women and 105 men). Patients were divided into the symptomatic group (with current or previous atherothrombotic symptoms, n=101) and at-risk group (with no current or previous symptoms, but aged over 55 years with at least two specified risk factors, n=109).
 
MAIN OUTCOME MEASURES. Patient characteristics were described, including the number of arterial beds affected, ankle brachial index, presence of risk factors, and medications taken.
 
RESULTS. Of the symptomatic patients, 30% had more than one arterial bed involved. A total of 55.4% of the symptomatic group and 18.4% of the at-risk group had abnormal ankle brachial index values. Lower ankle brachial indices were associated with a greater number of affected arterial beds. Diabetes mellitus and hypertension were the most prevalent risk factors in the at-risk group. Symptomatic patients were commonly treated with antihypertensive and antiplatelet agents, whereas at-risk patients were mostly treated with antihypertensive and antidiabetic agents. Only 20% of at-risk patients were taking antiplatelet agents.
 
CONCLUSIONS. Ankle brachial index is a useful tool for predicting those at risk of atherothrombosis. This simple measurement can be used as part of the screening process in the general practice. The role of antiplatelet agents in primary prevention of atherothrombotic events in at-risk patients deserves further attention.
 
Key words: Arteriosclerosis; Cardiovascular diseases; Epidemiologic factors; Hong Kong
 
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Two-port needlescopic cholecystectomy: prospective study of 100 cases

ABSTRACT

Hong Kong Med J 2005;11:30-5 | Number 1, February 2005
ORIGINAL ARTICLE
Two-port needlescopic cholecystectomy: prospective study of 100 cases
KW Lee, CM Poon, KF Leung, DWH Lee, CW Ko
Department of Surgery, Tuen Mun Hospital, Tsing Chung Koon Road, Tuen Mun, Hong Kong
 
 
OBJECTIVE. To test the feasibility of needlescopic cholecystectomy using a two-port technique with 3-mm miniaturised instruments.
 
DESIGN. Prospective study.
 
SETTING. Regional hospital, Hong Kong.
 
PATIENTS. One hundred consecutive patients undergoing elective cholecystectomy from September 2001 to August 2002.
 
INTERVENTION. Two-port needlescopic cholecystectomy all performed or supervised by a single laparoscopic surgeon.
 
MAIN OUTCOME MEASURES. Conversion of the procedure, the operating time, postoperative analgesic requirement, pain score using the 10-cm visual analog scale, complications, and the postoperative stay. To determine the technical difficulty of this new technique, the data from the first 50 patients were compared with those of the latter 50. Outcome variables were also compared with a group of 58 patients operated on with the standard two-port laparoscopic cholecystectomy in a previous randomised trial.
 
RESULTS. One conversion to open cholecystectomy was reported. Three patients required the enlargement of epigastric port to a size of 5 mm and six patients required an additional port to complete the operation. The median operating time was 62 minutes (range, 33-168 minutes). The median pain score was 3.5 (range, 0-9) and the median postoperative stay was 2 days (range, 1-14 days). Six patients had postoperative complications. When the first 50 patients were compared with the latter 50, there were no differences in the conversion rate, operating time, complication rate, and duration of hospital stay. However, the latter 50 patients had significantly lower pain scores (median, 3.5 vs 4.9; P=0.007) and faster resumption of diet (median, 5 vs 9 hours; P<0.001). The median operating time of needlescopic cholecystectomy was notably longer (62 vs 46 minutes; P<0.001) compared with that of the two-port laparoscopic cholecystectomy. Patients undergoing needlescopic cholecystectomy had a better resumption of diet (median, 5 vs 7 hours; P<0.001) and less postoperative pain (overall pain score, median, 3.5 vs 4.8; P=0.052) than the two-port laparoscopic cholecystectomy group. Pain scores at individual port sites were also lower in needlescopic cholecystectomy group (umbilical port: median, 3 vs 4.4, P=0.015; epigastric port: median, 2.0 vs 3.6, P=0.036).
 
CONCLUSION. Two-port needlescopic cholecystectomy is technically feasible and may further improve the surgical outcomes in terms of postoperative pain and cosmesis. It can be considered for routine practice by surgeons who are familiar with the two-port laparoscopic cholecystectomy technique.
 
Key words: Cholecystectomy, laparoscopic; Fiber optics; Laparoscopes; Miniaturization; Needles
 
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Laparoscopic adjustable gastric banding for the treatment of morbidly obese patients: early outcome in a Chinese cohort

ABSTRACT

Hong Kong Med J 2005;11:20-9 | Number 1, February 2005
ORIGINAL ARTICLE
Laparoscopic adjustable gastric banding for the treatment of morbidly obese patients: early outcome in a Chinese cohort
SKH Wong, WY So, PYP Yau, AKL Chan, S Lee, PN Chan, FCC Chow, SSC Chung
Department of Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong
 
 
OBJECTIVE. To evaluate the efficacy of laparoscopic adjustable gastric banding in the management of morbid obesity in a cohort of Chinese patients.
 
DESIGN. Cohort study.
 
SETTING. University teaching hospital, Hong Kong.
 
PATIENTS. From August 2002 to September 2003, 10 patients (6 male, 4 female) with a median age of 34 years (range, 23-48 years) underwent laparoscopic adjustable gastric banding to treat morbid obesity. Considerable co-existing diseases were present in 90% of the cases. We instituted a team approach that allowed every patient to see our dietitian, physician, psychiatrist (if necessary), and surgeon prior to deciding on the procedure to be used.
 
MAIN OUTCOME MEASURES. Excessive body weight loss, quality-of-life score (SF36), and co-morbidities improvement.
 
RESULTS. The 10 patients had a median weight of 127 kg (range, 115-196 kg) and median body mass index of 47 kg/m(2) [range, 38-67 kg/m(2)]. The operation was successful in all patients with a median operating time of 110 minutes (range, 75-240 minutes). The median hospital stay was 3 days (range, 3-4 days) and three of the patients required overnight observation in the intensive care unit because of severe sleep apnoea and asthma. The median follow-up period was 12 months (range, 1-18 months). The mean weight loss at 6, 12, and 18 months was 19.3, 22.4, and 25.9 kg, respectively. Mean percentage of excessive weight loss at 6, 12, and 18 months was 34.9%, 36.5%, and 40.5%, respectively. Unsatisfactory weight loss (<20 kg) occurred in three patients because of poor dietary compliance and non–follow-up. Surgery also considerably improved the patients’ co-morbidities (hypertension, diabetes, and obstructive sleep apnoea) and the quality of life.
 
CONCLUSION. In the short term, laparoscopic adjustable gastric banding is certainly an effective procedure for morbid obesity, which results in a substantial weight loss and improvement of co-existing morbidities. Longer follow-up will show whether this weight loss is maintainable.
 
Key words: Laparoscopy; Morbid obesity; Quality of life
 
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Screening of dementia in Chinese elderly adults by the clock drawing test and the time and change test

ABSTRACT

Hong Kong Med J 2005;11:13-9 | Number 1, February 2005
ORIGINAL ARTICLE
Screening of dementia in Chinese elderly adults by the clock drawing test and the time and change test
CC Chan, CY Yung, PC Pan
CC Chan, CY Yung, PC Pan
 
 
OBJECTIVES. To assess the usefulness, relative ease of administration, and patient acceptance of the clock drawing test as well as the time and change test for detecting dementia in Chinese elderly adults.
 
DESIGN. Prospective case-controlled study.
 
SETTING. Memory clinic and geriatric clinic of a district hospital, Hong Kong.
 
PARTICIPANTS. A convenient sample of 85 subjects aged 65 years or older attending the two clinics during the period from September 2002 to June 2003.
 
MAIN OUTCOME MEASURES. The clock drawing test scored according to Lam’s method; the time and change test with modification to the making change task; and the Chinese version of the Mini-Mental State Examination.
 
RESULTS. Demented subjects were matched with non-demented ones with respect to age, sex, educational level, and co-morbidity status. The clock drawing test had a comparable sensitivity (89.4%) but a lower specificity (47.1%) when compared with that of the Chinese version of the Mini-Mental State Examination (96.0 and 76.5%, respectively). In contrast, the time and change test had a lower sensitivity (62.7%) but higher specificity (94.1%). Both tests took significantly less time to complete than the Chinese version of the Mini-Mental State Examination. All except four subjects completed the clock drawing test while all subjects accepted the time and change test well.
 
CONCLUSIONS. The Chinese version of the Mini-Mental State Examination is still the best among the three tests despite the longer time to completion. The clock drawing test may be a good alternative to the Mini-Mental State Examination as an effective screening test for dementia when time does not permit. The time and change test, although time-saving, is not suitable to be used alone because of its low sensitivity.
 
Key words: Aged; Chinese; Dementia; Mental status schedule
 
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