Detection of amyloid plaques in patients with
post-stroke dementia
VCT Mok, WY Liu, A Wong
Department of Medicine and Therapeutics, The Chinese University of
Hong Kong
Key Messages
1. Using 11C-Pittsburgh Compound B (PiB) positron
emission tomography (PET), Alzheimer’s disease
pathology was found in one-fifth of patients with
post-stroke dementia.
2. Patients with Alzheimer’s disease pathology had a more progressive cognitive decline over 3 years after stroke or transient ischaemic attack.
3. In patients with post-stroke dementia, PiB PET may be used to guide treatment decision, as those with significant Alzheimer’s disease pathology may be more responsive to anti–Alzheimer’s disease drugs than those without.
2. Patients with Alzheimer’s disease pathology had a more progressive cognitive decline over 3 years after stroke or transient ischaemic attack.
3. In patients with post-stroke dementia, PiB PET may be used to guide treatment decision, as those with significant Alzheimer’s disease pathology may be more responsive to anti–Alzheimer’s disease drugs than those without.