B-cell signatures for disease flare and response
to pre-emptive immunosuppressive therapy in patients with lupus nephritis: abridged secondary publication
YHD Yap1, TM Chan1, S Yung1, S Wong2
1 Department of Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China
2 Department of Medicine and Geriatrics, United Christian Hospital, Hong Kong SAR, China
- Pre-emptive increase in immunosuppression in patients with lupus nephritis experiencing asymptomatic serological reactivation can reduce renal relapse and is well-tolerated.
- B-cell signatures can be modulated by pre-emptive treatment in patients with lupus nephritis and may serve as biomarkers for treatment response monitoring.