Hong Kong Med J 2024;30(Suppl 5):S40-6
Data driven identification and classification of Chinese medicine syndrome types among functional dyspepsia patients: latent tree analysis (abridged secondary publication)
L Ho1, Y Xu2, NL Zhang3, FF Ho1, IXY Wu4, S Chen5,6, X Liu5,6, CHL Wong7, JYL Ching8, PK Cheong8, WF Yeung9, JCY Wu10, VCH Chung1,7
1 School of Chinese Medicine, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China
2 School of Information Technology, Henan University of Chinese Medicine, Zhengzhou, Henan, China
3 Department of Computer Science and Engineering, School of Engineering, The Hong Kong University of Science and Technology, Hong Kong SAR, China
4 Xiangya School of Public Health, Central South University, Hunan, China
5 Department of Gastroenterology, Xiangya Hospital, Changsha, Hunan, China
6 Hunan International Scientific and Technological Cooperation Base of Artificial Intelligence Computer-Aided Diagnosis and Treatment for Digestive Disease, Changsha, Hunan, China
7 The Jockey Club School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China
8 Institute of Digestive Diseases, The Chinese University of Hong Kong, Hong Kong SAR, China
9 School of Nursing, Faculty of Health and Social Sciences, The Hong Kong Polytechnic University, Hong Kong SAR, China
10 Department of Medicine and Therapeutics, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China
 
 
  1. Eight pattern differentiation rules for functional dyspepsia were derived by latent tree analysis using data from 250 and 150 patients in Hong Kong and Hunan, respectively.
  2. At least one traditional Chinese medicine diagnostic pattern was identified in 70.7%, 73.6%, and 64.0% of the participants in the overall (n=400), Hong Kong (n=250), and Hunan (n=150) samples, respectively.
  3. Cold-heat complex (59.8%) and liver qi invading the stomach (77.1%) were the most prevalent diagnostic patterns in Hong Kong and Hunan samples, respectively.
  4. Spleen-stomach deficiency cold was highly likely to co-exist with spleen-stomach qi deficiency.
  5. Participants with severe anxiety tended to exhibit liver qi invading the stomach.