Hong Kong Med J 2020 Jun;26(3):267–8 | Epub 5 Jun 2020
Hong Kong Academy of Medicine. CC BY-NC-ND 4.0
LETTER TO THE EDITOR
Are face masks useful for limiting the spread of
COVID-19?
SK Law, PhD1,2,3; Albert WN Leung, PhD4; C Xu, PhD1
1 Key Laboratory of Molecular Target and Clinical Pharmacology, State
Key Laboratory of Respiratory Disease, School of Pharmaceutical
Sciences & Fifth Affiliated Hospital, Guangzhou Medical University,
Guangzhou, China
2 School of Chinese Medicine, Faculty of Medicine, The Chinese
University of Hong Kong, Hong Kong
3 Department of Science, School of Science and Technology, The Open
University of Hong Kong, Hong Kong
4 Asia-Pacific Institute of Aging Studies, Lingnan University, Hong Kong
Corresponding author: Prof C Xu (xcshan@163.com)
To the Editor—Coronavirus disease 2019 (COVID-19) is primarily spread through respiratory droplets
or close contact.1 Healthcare workers are advised to
wear surgical masks and other personal protective
equipment to prevent the spread of COVID-19. The
World Health Organization recommends that the
public need to wear a mask only when caring for a
person with suspected COVID-19,2 and emphasises
frequent handwashing and social distancing
(avoiding close contact within 1 to 2 m) in order to
save the limited supply of available masks for carers
and healthcare workers who rely on them.3 Further
to these recommendations, some Asian countries
such as China, Japan, South Korea and Thailand, and
also Hong Kong, face masks are also recommended
in crowded places or on public transport. Although
there is limited evidence that face masks are effective
in protecting the wearer from infection, wearing face
masks can prevent transmission from an infected
person, including those who may be asymptomatic
or presymptomatic.4
Recently, researchers from The University
of Hong Kong have found the ability of surgical
masks to reduce seasonal coronavirus in respiratory
droplets and aerosols.5
Some international studies have also
demonstrated the efficacy of surgical masks in
preventing respiratory virus transmission. For
example, in 2008, a randomised, controlled clinical
trial study from Australia showed that surgical
masks had efficacious protective efficacy of over
80% against the transmission of respiratory viruses.6
In 2011, Jefferson et al7 found that wearing a mask
or N95 respirator might reduce respiratory virus
infection. More recently, researchers from South
Korea studied four patients infected with COVID-19 and found that surgical masks helped prevent
the spread of severe acute respiratory syndrome
coronavirus 2 and reduced the viral load of a cough.8
On 3 April, the Centers for Disease Control and
Prevention of the United States suggested wearing
cloth face-coverings in a public area, in addition
to social distancing, to prevent transmission in the
community.9
Face mask wearing can prevent transmission
of COVID-19 in the general population by limiting
the spread from infected individuals, including those
who are asymptomatic or pre-symptomatic.
Author contributions
All authors contributed to the concept of the study, acquisition and analysis of the data, drafting of the manuscript, and critical
revision of the manuscript for important intellectual content.
All authors had full access to the data, contributed to the
study, approved the final version for publication, and take
responsibility for its accuracy and integrity.
Conflicts of interest
The authors have no conflicts of interest to disclose.
Funding/support
The authors received no funding source/grants or other materials support for this work.
References
1. Modes of transmission of virus causing COVID-19:
implications for IPC precaution recommendations. 29
March 2020. Available from: https://www.who.int/news-room/commentaries/detail/modes-of-transmission-of-virus-causing-covid-19-implications-for-ipc-precaution-recommendations.
Accessed 16 Apr 2020.
2. Coronavirus disease (COVID-19) advice for the public:
when and how to use masks. 17 March 2020. Available
from: https://www.who.int/emergencies/diseases/novel-coronavirus-
2019/advice-for-public/when-and-how-to-use-masks. Accessed 16 Apr 2020.
3. To mask or not to mask: WHO makes U-turn while US,
Singapore abandon pandemic advice and tell citizens to
start wearing masks. 4 April 2020. Available from: https://www.scmp.com/news/hong-kong/health-environment/article/3078437/mask-or-not-mask-who-makes-u-turn-while-us. Accessed 16 Apr 2020.
4. Feng S, Shen C, Xia N, Song W, Fan M, Cowling BJ.
Rational use of face masks in the COVID-19 pandemic.
Lancet Respir Med 2020 Mar 20. Epub ahead of print. Crossref
5. Leung NH, Chu DK, Shiu EY, et al. Respiratory virus
shedding in exhaled breath and efficacy of face masks. Nat
Med 2020 Apr 3. Epub ahead of print. Crossref
6. Maclntyre CR, Dwyer D, Seale H, et al. The first
randomized, controlled clinical trial of mask use in
households to prevent respiratory virus transmission. Int J Infect Dis 2008;12(Suppl 1):E328. Crossref
7. Jefferson T, Del Mar CB, Dooley L, et al. Physical
interventions to interrupt or reduce the spread of
respiratory viruses. Cochrane Database Syst Rev
2011;(7):CD006207. Crossref
8. Bae S, Kim MC, Kim JY, et al. Effectiveness of surgical
and cotton masks in blocking SARS-CoV-2: A controlled comparison in 4 Patients. Ann Int Med 2020 Apr 6. Epub
ahead of print. Crossref
9. Recommendation regarding the use of cloth face coverings,
especially in areas of significant community-based
transmission. 3 April 2020. Available from: https://www.
cdc.gov/coronavirus/2019-ncov/prevent-getting-sick/
cloth-face-cover.html. Accessed 16 Apr 2020.