Sonodynamic bactericidal efficacy of hypocrellin A and B against methicillin-resistant Staphylococcus aureus
AWN Leung1, M Ip2, CS Xu1, XN Wang1, PT Yung3, HY Hua1
1 School of Chinese Medicine, The Chinese University of Hong Kong
2 Department of Microbiology, The Chinese University of Hong Kong
3 Department of Electronic Engineering, The Chinese University of Hong Kong
1. Hypocrellin A and B have significant
bactericidal activity against methicillin-resistant
Staphylococcus aureus (MRSA).
2. Sonodynamic treatment of hypocrellin A/B inhibits protein synthesis of MRSA.
3. Hypocrellin A/B–mediated sonodynamic action causes notable damage to membrane integrity, membrane potential, and ultrastructure of MRSA.
2. Sonodynamic treatment of hypocrellin A/B inhibits protein synthesis of MRSA.
3. Hypocrellin A/B–mediated sonodynamic action causes notable damage to membrane integrity, membrane potential, and ultrastructure of MRSA.