Diabetes has been evolving as a worldwide epidemic and constitutes one of the important global burdens of diseases. The reference framework for diabetes care has been produced by the Task Force on Conceptual Model and Preventive Protocols of the Working Group on Primary Care, so as to enhance the clinical care for diabetes patients. The guideline emphasises a comprehensive, coordinated approach with interdisciplinary collaboration between major primary care stakeholders throughout the life of the patient. It was developed by drawing on evidence from international literature with input from primary care physicians, as well as specialists including endocrinologists, doctors from public and private sectors, as well as representatives from patient groups. This article presents the latest updates on the management of diabetes, ranging from its epidemiology, patient education, prevention, early identification, complication monitoring, drug treatment, patient empowerment, and rehabilitation. It is anticipated that the adoption of this framework will contribute to better control of this chronic condition in the primary care setting.