Hong Kong Med J 2023;29(Suppl 7):S24-30
Gut microbiota across early stages of synucleinopathy: abridged secondary publication
YK Wing1, J Zhang1, KF To2, CTV Mok3, SMS Ng4, HS Wong3, XS Li5
1 Department of Psychiatry, The Chinese University of Hong Kong, Hong Kong SAR, China
2 Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Hong Kong SAR, China
3 Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong SAR, China
4 Department of Surgery, The Chinese University of Hong Kong, Hong Kong SAR, China
5 Department of Psychology, The University of Hong Kong, Hong Kong SAR, China
 
 
  1. Gut dysbiosis is present in individuals with early and prodromal stages of synucleinopathy, including patients with rapid eye movement sleep behaviour disorder and their first-degree relatives who exhibit earlier prodromal features of the disorder.
  2. Gut microbiome features might be a promising target for the early prevention and treatment of synucleinopathy.